ABSTRACT
Bambusa arundinacea family Graminae is highly reputed ayurvedic medicinal tree commonly known as the Bamboo. It is tall sized tree growing throughout India, moist parts of India. It also occurs in Sri Lanka, Malaya, Peru and Myanmar. The different parts of this plant contain silica, Cholin, betain, cynogenetic glycosides, albuminoids, Oxalic acid, reducing sugar, resins, waxes, benzoic acid, Arginine, cysteine, histidine, niacin, riboflavin, thiamine, Protein, gluteline, contains lysine, methionine, betain, cholin, proteolytic enzyme, nuclease, urease. Various parts of this plant such as Leaf, root, shoot and seed possess Anti-inflammatory, Antiulcer, Anti-diabetic, Anti-oxidant, anthelmintic, astringent, emmengogue activity. Various phytopharmacological evaluations have been reported in this literature for the important potential of the Bambusa arundinacea.
ABSTRACT
Randia dumetorum family Rubiaceae is highly reputed ayurvedic medicinal tree commonly known as the Mainphal, Mindhal. A large deciduous thorny shrub grows up to 5 meters of height. It occurs in almost throughout India up to 4,000 ft attitude. It is found in Himalaya from jammu east words ascending to 1300 and from the Kashmir to east word’s up to 4000. It is seen in Gujarat, Tamilnadu forest of Dehradun, Suralik range, Bengal, Bihar, Orrisa & South Maharashtra and costal districts of south India. In dry deciduous forests in India. Root bark of Randia dumetorum contains triterpene, -1-keto-3-hydroxyoleanane, Bark of Randia dumetorum contains mannitol, saponins, coumarin glycosides, Leaves contain an iridoid-10- methylixoside. An iridoid glycoside, Ripe fruit contains glycosides, randioside A, mollisidial triterpenoid glycosides and randianin, six saponins-dumetoronins A to F. It cures abscess, ulcers, inflammation, wounds, tumours, skin diseases and have antibacterial activity. The pulp of fruit is believed by many practitioners to also have anthelmintic properties, and also used as an abortiffcient as folklore remedy. Various phytopharmacological evaluations have been reported in this literature for the important potential of the Randia dumetorum.
ABSTRACT
Coriandrum Sativum family Umbelliferae is highly reputed ayurvedic medicinal tree commonly known as the Dhanyaka. It is small sized tree growing throughout India, Italy. Netherlands, Central and Eastern Europe, China and Bangladesh. The different parts of this plant contain monoterpenes, α-pinene, limpnene, γ-terpinene, p-cymene, borneol, citronellol, camphor, geraniol, coriandrin, dihydrocoriandrin, coriandronsA-E, flavonoids and essential oils. Various parts of this plant such as seed, leaves, flower and fruit, possess Diuretic, Antioxidant Activity, Ant-diabetic Anti-convulsant activity, Sedative Hypnotic Activity, Anti-microbial Activity, Anti mutagenic, Anthelmintic activity. Various phytopharmacological evaluations have been reported in this literature for the important potential of the Coriandrum sativum.
ABSTRACT
Now day diabetes is very common world wild disease. Basically two type of diabetes: Type-I and Type-II. Various short term complications like diabetec ketoacidosis, hyperosmolar nonketotic coma and hypoglycemia and long term complication like diabetec neuropathy, diabetec retinopathy, diabetec nepheropathy, diabetec microangiopathy, heart disease and stroke occur due to diabetes mellitus. Cardiovascular complication mainly occurs by either increase of glucose by activation of protein kinase, rennin angeotensin system, advance glycation endproduct theory i.e. AGE-RAGE or by metabolic syndrome and insulin resistance mechanism which precipitates obesity, physical inactivity and genetic susceptibility. Insulin secretion is decreases with advancing age which may be accelerate by genetic factor. Insulin resistance led to onset of Type-II diabetes mellitus and is commonly associated with other cardio vascular risk factors like dysbetalipidema, hypertension and prothombic factor. Evaluation of these major risk factors is very necessary. Predisposing risk factors are body weight and fat distribution in the body, physical activity and family history. Detection of clinical and sub clinical cardiovascular disease in diabetic patient. Evaluation of factor such as a stress testing for coronary heart disease, non-invasive evaluation of cardiac function, evaluation of autonomic dysfunction, detection of sub clinical cardio vascular disease and it treated by changing life style or by using insulin matrix.
ABSTRACT
Dissolution test is required to study the drug release from the dosage form and its in vivo performance. Dissolution test is used to asses the lot to lot quality of drug product. The development and validation of dissolution procedures is of paramount importance during development of new formulation and in quality control. The dissolution procedure must be properly developed and validated. The objective of this paper is to review the development and validation of dissolution procedure(s) and to provide practical approaches for determining specificity, linearity, range, accuracy, precision, limit of detection, limit of quantitation and robustness of methods. Developing and validating dissolution test procedures can be a challenging process, on multiple fronts. Methods must be developed and validated not just for the dissolution test procedure itself, but also for any assay used to evaluate the test results.
ABSTRACT
Anxiety has much impact on human as well as animal behaviors. For evaluation of anxiolytic drug require both clinical and biological aspect of anxiety. We review the existing experimental models of anxiety like elevated plus maze apparatus, light dark model, open field apparatus, holeborad apparatus in order to promote further understanding of neurobiological aspects of anxiety.